Yes, we can

private static Bitmap bmpScreenshot;
private static Graphics gfxScreenshot;

// If the user has chosen a path where to save the screenshot
if (saveScreenshot.ShowDialog() == DialogResult.OK)
{
// Hide the form so that it does not appear in the screenshot
this.Hide();

// Set the bitmap object to the size of the screen
bmpScreenshot = new Bitmap(Screen.PrimaryScreen.Bounds.Width,Screen.Pr imaryScreen.Bounds.Height, PixelFormat.Format32bppArgb);

// Create a graphics object from the bitmap
gfxScreenshot = Graphics.FromImage(bmpScreenshot);

// Take the screenshot from the upper left corner to the right bottom corner
gfxScreenshot.CopyFromScreen(Screen.PrimaryScreen. Bounds.X, Screen.PrimaryScreen.Bounds.Y, 0, 0, Screen.PrimaryScreen.Bounds.Size, CopyPixelOperation.SourceCopy);

// Save the screenshot to the specified path that the user has chosen
bmpScreenshot.Save(saveScreenshot.FileName, ImageFormat.Png);

// Show the form again
this.Show();
}