DotNetNuke Multiple Portal Method

DotNetNuke allows you to use a single hosting account for multiple domain names. Within DotNetNuke, you simply create a portal for each of the domain names. You no longer have to pay several hosting bills for hosting your websites, DotNetNuke can display the content for each of your domain names from one installation, ie. one hosting account (see figure 2).

How it works (below I gave the basic steps)
1) Point Domain names to Hosting Providers’ server
Purchase your domain names from a domain name registrar and point the domain names to your hosting providers’ server (using the DNS settings).

2) Point Domain Names to your single DotNetNuke Installation
In your Hosting Providers control panel, go into the IIS settings and adjust the Host Header settings to point the domain name to the IP address of your DotNetNuke installation.

3) Create portals in DotNetNuke
In DotNetNuke create multiple portals for each of your domain names. The Portal Alias settings pick up the domain name and point it to the correct portal.